Name | BAY1238097 |
Synonyms | BAY1238097 3H-2,3-Benzodiazepine-3-carboxamide, 4,5-dihydro-7,8-dimethoxy-N,4-dimethyl-1-[4-(4-methyl-1-piperazinyl)phenyl]-, (4S)- |
CAS | 1564268-08-1 |
Molecular Formula | C25H33N5O3 |
Molar Mass | 451.56 |
Density | 1.22±0.1 g/cm3(Predicted) |
pKa | 15.43±0.60(Predicted) |
Storage Condition | 2-8℃ |
Use | BAY1238097 is a potent, selective inhibitor of BET binding to histones by down-regulating the c-Myc level and downstream transcriptome in AML (acute myeloid leukemia) and MM (multiple myeloma). The model showed strong anti-proliferative activity (I |